Basic and Clinical Sciences (BCSE) Practice Exam

A characteristic feature of erythema multiforme is the presence of target-like lesions, which are also referred to as "target lesions." These lesions are typically well-defined, with a central zone that may be darker in color surrounded by a pale halo and an outer red ring. This classic appearance of the target lesions is key in diagnosing erythema multiforme and differentiating it from other skin conditions.

While widespread vesicular lesions can occur in conditions such as herpes simplex infection, they are not typical of erythema multiforme. Chronic pruritus may accompany various dermatological conditions, but it's not uniquely associated with the target lesions seen in erythema multiforme. Additionally, ulcerative lesions on mucous membranes might be associated with other disorders, such as Stevens-Johnson syndrome or other severe reactions, rather than the hallmark of erythema multiforme, which is primarily indicated by its characteristic target lesions.