Basic and Clinical Sciences (BCSE) Practice Exam

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In which part of the human lung is anatomical dead space primarily located?

  1. Trachea and bronchi

  2. Terminal bronchioles

  3. Alveolar sacs

  4. Capillary beds

The correct answer is: Trachea and bronchi

Anatomical dead space refers to the parts of the respiratory system where gas exchange does not occur, primarily comprising the airways down to the terminal bronchioles. The primary location of anatomical dead space is in the trachea and bronchi. These structures conduct air to the lungs but do not participate in the diffusion of oxygen and carbon dioxide. This means that while air passes through the trachea and bronchi, the gas exchange happens only in the alveoli, which are the functional units of the lung. In contrast, the terminal bronchioles do not contribute to anatomical dead space since they lead directly to the alveolar sacs where gas exchange can begin. The alveolar sacs are the sites of exchange and therefore are not part of the dead space. Capillary beds, while essential in the exchange of gases, are also not part of anatomical dead space; they are located in the alveolar walls, where oxygen and carbon dioxide are exchanged with the blood. Thus, the correct understanding of where anatomical dead space is located emphasizes the importance of the trachea and bronchi in this concept of respiratory anatomy.