Basic and Clinical Sciences (BCSE) Practice Exam

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What is the general prognosis for malignant pleural effusions in lung cancer?

  1. Typically curable

  2. May require aggressive management

  3. Generally considered incurable

  4. Usually resolves spontaneously

The correct answer is: Generally considered incurable

The prognosis for malignant pleural effusions in lung cancer is generally considered incurable due to the underlying nature of the disease. Malignant pleural effusions typically arise from advanced lung cancer and are indicative of a poor prognosis, as they suggest that cancer has spread beyond the primary tumor site. Lung cancer, particularly in its advanced stages, often leads to significant complications and challenges in treatment, making it less likely that the effusion can be resolved or cured completely. These effusions are caused by the infiltration of cancerous cells into the pleural space, which not only complicates the person's clinical picture but also reflects the systemic advancement of the disease. Patients with malignant pleural effusions usually face a limited life expectancy, and management strategies often focus on palliative care rather than curative interventions. While some may require aggressive management to relieve symptoms, the prognosis remains poor. Spontaneous resolution is rare in malignant cases, as the underlying cancer persists and continues to drive the formation of pleural effusions. As such, recognizing the generally incurable nature of malignant pleural effusions in the context of lung cancer is crucial for both patient management and setting realistic expectations regarding outcomes.