Basic and Clinical Sciences (BCSE) Practice Exam

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Which measurement is commonly used to assess dead space in clinical practice?

  1. Arterial blood gases

  2. End-tidal carbon dioxide levels

  3. Lung volumes

  4. Peak flow rates

The correct answer is: End-tidal carbon dioxide levels

The assessment of dead space—areas of the lungs where ventilation occurs without perfusion—often involves the measurement of end-tidal carbon dioxide (ETCO2) levels. ETCO2 is the concentration of carbon dioxide being expelled at the end of exhalation and provides essential information about ventilation and perfusion balance in the lungs. In conditions with increased dead space, such as pulmonary embolism or chronic obstructive pulmonary disease (COPD), the ETCO2 levels can be lower than normal due to the mismatch between ventilation and perfusion. While arterial blood gases provide information about the overall gas exchange and acid-base balance in the blood, they do not directly indicate dead space. Lung volumes can provide insights into overall lung function but are less specific for measuring dead space. Peak flow rates measure the maximum speed of expiration and are typically used to assess airway obstruction rather than dead space directly. Thus, end-tidal carbon dioxide levels are specifically valuable for evaluating dead space in clinical scenarios.