Basic and Clinical Sciences (BCSE) Practice Exam

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Which nerves are responsible for the innervation of the diaphragm?

  1. C1, 2, 3

  2. C3, 4, 5

  3. T8, T9, T10

  4. T1, T2, T3

The correct answer is: C3, 4, 5

The diaphragm, a critical muscle for respiration, is primarily innervated by the phrenic nerve, which arises from the cervical spinal roots C3, C4, and C5. This nerve plays an essential role in controlling the diaphragm's contractions, enabling breathing. Understanding the significance of the cervical nerves involved is crucial. The phrenic nerve's pathway, originating mainly from these cervical roots, ensures that signals are accurately transmitted to the diaphragm. This means that injury or damage to any part of this nerve, or to its roots, can significantly impair respiratory function, leading to respiratory distress. In contrast, the other set of nerves mentioned does not innervate the diaphragm. While the upper cervical nerves (C1, C2, and part of C3) are involved in various head and neck functions, they do not contribute directly to diaphragmatic movement. The thoracic nerves (T8, T9, T10, T1, T2, and T3) are primarily involved in abdominal and intercostal muscle innervation, with no direct role in diaphragm contraction. Therefore, understanding the specific contribution of C3, C4, and C5 to diaphragm innervation highlights the importance of these roots in maintaining effective respiratory function