Basic and Clinical Sciences (BCSE) Practice Exam

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Which of the following is not a consequence of hyponatremia?

  1. Dizziness

  2. Muscle weakness

  3. Increased thirst

  4. Headache

The correct answer is: Increased thirst

In the context of hyponatremia, increased thirst is not typically a direct consequence. Hyponatremia, defined as a low concentration of sodium in the blood, often arises from conditions that involve excess water intake or loss of sodium, resulting in symptoms primarily due to cellular swelling and neurological effects. Dizziness, muscle weakness, and headache are common symptoms associated with hyponatremia. The low sodium levels lead to an imbalance in fluid distribution between the intracellular and extracellular compartments, affecting the function of muscles and the central nervous system. These symptoms arise due to the inability of cells to maintain osmotic equilibrium, causing various degrees of impairment in bodily functions. In contrast, increased thirst is typically a response to hypernatremia, where there is a higher concentration of sodium in the blood that leads to dehydration. In a state of hyponatremia, the body is usually retaining fluid, and the thirst mechanism is often suppressed rather than stimulated. Hence, the option indicating increased thirst stands out as the correct response for consequences that are not associated with hyponatremia.